Educación Médica Continua

The first language of baby is touch. Módulo 1: EV.E.I.L.S sobre la piel normal + percepción sensorial de la piel.

EV.E.I.L.S* programme (EValuation of Early Infant Life: the Skin): 15 years of Mustela® research into the first study of children’s skin from birth onwards.

In partnership with a number of renowned dermatology researchers with clinical and in vitro studies of 14 patents and 69 scientific publications.1-4

Analysis of baby’s skin physiology: from the cutaneous barrier right down to the cellular level and the lowest-lying layers of the epidermis.

Mustela® baby & child range: completely reformulated, designed and patented a brand-new natural active ingredient: Avocado Perseose®.

*EV.E.I.L.S PROGRAMME: disponible sur https://www.expanscience.com/en/skin-health/products-babies-children. [Consulté le 24 décembre 2020].

Skin anatomy and physiology

Normal infant skin: Updates on major Discoveries Cf other kit

Infant skin is functionally and structurally different to that of adults

Sense of touch: Tactile receptors

• Mechanoreceptors -> Sense of touch
• Nociceptors -> Pain sensation
• Thermoreceptors -> Temperature variations

Sense of touch: Differences between glabrous and non glabrous skin

Organization of touch

PROJECTION OF AFFERENT NERVOUS FIBERS TOWARDS CENTRAL NERVOUS SYSTEM

Links between skin and brain development

REFERENCIAS:

Fluhr JW et al., Infant epidermal skin physiology: adaptation after birth.

Br J Dermatol 2012;166,:483–490

Fluhr JW et al., Age-Dependent Transformation of Skin Biomechanical Properties and Micromorphology during Infancy and Childhood. J Invest Dermatol 2019; 139: 464-466.

Fluhr JW et al., Development and organization of human stratum corneum after birth: electron microscopy isotropy score and immunocytochemical corneocyte labelling as epidermal maturation’s markers in infancy. Br J Dermatol 2014;171:978–986.

In vitro patented Stelaskin® : Skin barrier function is in construction and vulnerable facing aggressions, in which epidermal stem cells are mobilized

Kolarsick PAJ, et al.Anatomy and Physiology of the Skin. JDNA 2011;3(4): 203-213.

Delmas P, et al. Molecular mechanisms of mechanotransduction in mammalian sensory neurons, Nature Reviews Neuroscience 2011;12,:139–153.

Bourinet E, et al. Calcium-permeable ion channels in pain signaling.Physiol Rev 2014;94(1):81-140.